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| Name | NFL Team | Bye | FF Team | G | Pts | PPG | Yards | TDs | INT | Fumbles | 2pt |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Joe Burrow | CIN | 6 | RL | 8 | 181 | 22.63 | 2463 | 26 | 6 | 1 | 0 |
| Josh Allen | BUF | 7 | TMC | 8 | 147 | 18.38 | 2313 | 21 | 6 | 1 | 1 |
| Jordan Love | GB | 11 | ANJ | 9 | 155 | 17.22 | 2641 | 21 | 6 | 1 | 2 |
| Brock Purdy | SF | 8 | ANJ | 8 | 132 | 16.5 | 2181 | 19 | 5 | 0 | 1 |
| C.J. Stroud | HOU | 8 | GW | 8 | 132 | 16.5 | 2351 | 17 | 2 | 2 | 1 |
| Kirk Cousins | MIN | 6 | MM | 9 | 147 | 16.33 | 2347 | 22 | 8 | 0 | 1 |
| Drake Maye | NE | 11 | NOR | 9 | 135 | 15 | 2501 | 21 | 11 | 2 | 1 |
| Trevor Lawrence | JAC | 7 | OC | 8 | 118 | 14.75 | 2011 | 18 | 4 | 1 | 0 |
| Jared Goff | DET | 6 | AE | 8 | 118 | 14.75 | 2154 | 16 | 2 | 1 | 0 |
| Bryce Young | CAR | 5 | MM | 8 | 116 | 14.5 | 2244 | 17 | 6 | 2 | 0 |
| Dak Prescott | DAL | 14 | SOB | 9 | 125 | 13.89 | 2483 | 17 | 5 | 1 | 2 |
| Tyler Shough | NO | 8 | SOB | 8 | 108 | 13.5 | 2148 | 16 | 6 | 3 | 0 |
| Patrick Mahomes | KC | 5 | GW | 8 | 106 | 13.25 | 2122 | 15 | 4 | 1 | 0 |
| Matthew Stafford | LAR | 11 | NT | 9 | 110 | 12.22 | 2393 | 16 | 9 | 0 | 0 |
| Caleb Williams | CHI | 10 | RMO | 6 | 73 | 12.17 | 1691 | 10 | 5 | 0 | 0 |
| Jayden Daniels | WAS | 7 | NT | 6 | 70 | 11.67 | 1502 | 9 | 0 | 1 | 1 |
| Jalen Hurts | PHI | 10 | CRU | 5 | 55 | 11 | 1040 | 9 | 3 | 0 | 0 |
| Drew Lock | SEA | 11 | 3 | 33 | 11 | 626 | 5 | 0 | 0 | 0 | |
| Jaxson Dart | NYG | 8 | 2 | 22 | 11 | 304 | 3 | 0 | 0 | 0 | |
| Lamar Jackson | BAL | 13 | GW | 5 | 52 | 10.4 | 1111 | 7 | 1 | 1 | 0 |
| Aaron Rodgers | PIT | 9 | AE | 8 | 82 | 10.25 | 1894 | 13 | 6 | 1 | 1 |
| Geno Smith | NYJ | 13 | OC | 9 | 87 | 9.67 | 2132 | 12 | 3 | 2 | 2 |
| Bo Nix | DEN | 10 | 9 | 85 | 9.44 | 1846 | 13 | 4 | 2 | 3 | |
| Sam Darnold | SEA | 11 | 7 | 63 | 9 | 1550 | 10 | 9 | 0 | 2 | |
| Gardner Minshew | ARI | 14 | 2 | 18 | 9 | 358 | 3 | 0 | 0 | 0 | |
| Michael Penix Jr. | ATL | 11 | 7 | 62 | 8.86 | 1509 | 10 | 6 | 1 | 3 | |
| Jacoby Brissett | BAL | 13 | RMO | 8 | 70 | 8.75 | 1813 | 11 | 7 | 0 | 0 |
| Marcus Mariota | WAS | 7 | 3 | 24 | 8 | 389 | 4 | 0 | 0 | 0 | |
| Jameis Winston | NYG | 8 | CRU | 7 | 52 | 7.43 | 1089 | 9 | 5 | 1 | 0 |
| Deshaun Watson | CLE | 11 | 8 | 59 | 7.38 | 2023 | 8 | 3 | 3 | 1 | |
| Tyler Huntley | BAL | 13 | 5 | 32 | 6.4 | 803 | 5 | 1 | 1 | 0 | |
| Cam Ward | TEN | 9 | 8 | 50 | 6.25 | 1595 | 8 | 5 | 1 | 3 | |
| Malik Willis | MIA | 6 | 8 | 49 | 6.13 | 1628 | 9 | 6 | 3 | 1 | |
| Shedeur Sanders | CLE | 11 | 3 | 18 | 6 | 327 | 2 | 0 | 0 | 0 | |
| DJ Uiagalelei | LAC | 7 | 1 | 6 | 6 | 24 | 1 | 0 | 0 | 0 | |
| Kyler Murray | MIN | 6 | 6 | 35 | 5.83 | 1189 | 5 | 3 | 0 | 1 | |
| Case Keenum | CHI | 10 | 3 | 17 | 5.67 | 365 | 3 | 1 | 1 | 0 | |
| Athan Kaliakmanis | WAS | 7 | 1 | 5 | 5 | 202 | 1 | 1 | 0 | 0 | |
| Carson Wentz | MIN | 6 | 3 | 14 | 4.67 | 362 | 3 | 2 | 1 | 1 | |
| Tanner McKee | PHI | 10 | 3 | 10 | 3.33 | 664 | 2 | 2 | 1 | 0 | |
| Baker Mayfield | TB | 10 | CRU | 6 | 18 | 3 | 1002 | 4 | 4 | 3 | 1 |
| J.J. McCarthy | NYG | 8 | 4 | 12 | 3 | 673 | 1 | 1 | 0 | 1 | |
| Daniel Jones | IND | 13 | 9 | 26 | 2.89 | 1808 | 7 | 10 | 3 | 0 | |
| Justin Herbert | LAC | 7 | 8 | 22 | 2.75 | 1781 | 6 | 11 | 2 | 0 | |
| Jalon Daniels | TB | 10 | 5 | 11 | 2.2 | 621 | 3 | 5 | 0 | 0 | |
| Joe Milton | PHI | 10 | 1 | 2 | 2 | 233 | 0 | 0 | 1 | 1 | |
| Kyle Allen | BUF | 7 | 2 | 0 | 0 | -4 | 0 | 0 | 0 | 0 | |
| Mason Rudolph | PIT | 9 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | |
| Stetson Bennett | LAR | 11 | 2 | 0 | 0 | 22 | 0 | 0 | 0 | 0 | |
| Anthony Richardson | IND | 13 | 1 | 0 | 0 | 12 | 0 | 0 | 0 | 0 | |
| Spencer Rattler | NO | 8 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Kenny Pickett | CAR | 5 | 3 | 0 | 0 | 82 | 0 | 0 | 0 | 0 | |
| Mac Jones | SF | 8 | 2 | 0 | 0 | -5 | 0 | 0 | 0 | 0 | |
| Quinn Ewers | JAC | 7 | 2 | 0 | 0 | 8 | 0 | 0 | 0 | 0 | |
| Joshua Dobbs | DET | 6 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Joe Flacco | CIN | 6 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Cole Payton | PHI | 10 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Fernando Mendoza | LV | 13 | TMC | 1 | 0 | 0 | 51 | 0 | 0 | 0 | 0 |
| Tommy DeVito | NE | 11 | 2 | 0 | 0 | 53 | 0 | 0 | 0 | 0 | |
| Davis Mills | HOU | 8 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | |
| Max Brosmer | MIN | 6 | 1 | 0 | 0 | 58 | 0 | 0 | 0 | 0 | |
| Tyrod Taylor | GB | 11 | 2 | 0 | 0 | -2 | 0 | 0 | 0 | 0 | |
| Nick Mullens | JAC | 7 | 1 | 0 | 0 | -3 | 0 | 0 | 0 | 0 | |
| Justin Fields | KC | 5 | 2 | -2 | -1 | -1 | 0 | 0 | 1 | 0 | |
| Tyson Bagent | CHI | 10 | 3 | -3 | -1 | 427 | 0 | 3 | 0 | 0 | |
| Andy Dalton | ATL | 11 | 1 | -2 | -2 | 0 | 0 | 1 | 0 | 0 | |
| Tua Tagovailoa | ATL | 11 | 1 | -2 | -2 | 34 | 0 | 1 | 0 | 0 | |
| Cooper Rush | 2 | -4 | -2 | 249 | 1 | 4 | 1 | 0 | |||
| Jack Strand | ATL | 11 | 1 | -4 | -4 | 75 | 0 | 1 | 1 | 0 | |
| Joe Fagnano | BAL | 13 | 2 | -8 | -4 | 167 | 0 | 3 | 1 | 0 |