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| Name | NFL Team | Bye | FF Team | G | Pts | PPG | Yards | TDs | INT | Fumbles | 2pt |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Lamar Jackson | BAL | 14 | GW | 14 | 276 | 19.71 | 4323 | 37 | 3 | 5 | 1 |
| Joe Burrow | CIN | 12 | TR | 14 | 258 | 18.43 | 4135 | 37 | 8 | 4 | 0 |
| Josh Allen | BUF | 12 | TMC | 14 | 257 | 18.36 | 3879 | 36 | 5 | 2 | 1 |
| Baker Mayfield | TB | 11 | CRU | 14 | 233 | 16.64 | 3883 | 35 | 14 | 2 | 1 |
| Jared Goff | DET | 5 | AE | 14 | 219 | 15.64 | 3826 | 31 | 10 | 0 | 0 |
| Jalen Hurts | PHI | 5 | MM | 14 | 210 | 15 | 3481 | 32 | 5 | 5 | 0 |
| Sam Darnold | MIN | 6 | 14 | 195 | 13.93 | 3724 | 30 | 11 | 4 | 0 | |
| Jordan Love | GB | 10 | SOB | 12 | 157 | 13.08 | 3028 | 24 | 11 | 0 | 2 |
| Jayden Daniels | WAS | 14 | TR | 14 | 179 | 12.79 | 3701 | 23 | 6 | 0 | 3 |
| Tua Tagovailoa | MIA | 6 | NOR | 10 | 127 | 12.7 | 2702 | 18 | 7 | 2 | 2 |
| Russell Wilson | PIT | 9 | ANJ | 8 | 93 | 11.63 | 1969 | 14 | 3 | 3 | 0 |
| Bo Nix | DEN | 14 | AE | 14 | 162 | 11.57 | 3301 | 25 | 11 | 0 | 0 |
| Patrick Mahomes | KC | 6 | CRU | 14 | 158 | 11.29 | 3612 | 23 | 11 | 0 | 0 |
| Aaron Rodgers | NYJ | 12 | SOB | 14 | 156 | 11.14 | 3356 | 23 | 8 | 1 | 2 |
| Derek Carr | NO | 12 | 10 | 104 | 10.4 | 2216 | 16 | 5 | 0 | 1 | |
| Brock Purdy | SF | 9 | ANJ | 13 | 135 | 10.38 | 3459 | 19 | 9 | 3 | 0 |
| Kyler Murray | ARI | 11 | RL | 14 | 136 | 9.71 | 3541 | 19 | 8 | 3 | 1 |
| Dak Prescott | DAL | 7 | GW | 8 | 77 | 9.63 | 2032 | 12 | 8 | 1 | 0 |
| Justin Herbert | LAC | 5 | GW | 14 | 132 | 9.43 | 3183 | 18 | 2 | 2 | 1 |
| Trevor Lawrence | JAC | 12 | SB | 10 | 94 | 9.4 | 2159 | 14 | 7 | 1 | 3 |
| Matthew Stafford | LAR | 6 | RL | 14 | 131 | 9.36 | 3492 | 19 | 7 | 2 | 0 |
| Caleb Williams | CHI | 7 | TMC | 14 | 125 | 8.93 | 3339 | 17 | 5 | 4 | 3 |
| Drake Maye | NE | 14 | MM | 10 | 88 | 8.8 | 2257 | 14 | 9 | 4 | 2 |
| Geno Smith | SEA | 10 | SB | 14 | 123 | 8.79 | 3854 | 16 | 13 | 0 | 0 |
| Jameis Winston | CLE | 10 | ANJ | 12 | 99 | 8.25 | 2204 | 14 | 12 | 2 | 4 |
| C.J. Stroud | HOU | 14 | NOR | 14 | 115 | 8.21 | 3451 | 17 | 9 | 4 | 0 |
| Joe Flacco | IND | 14 | 6 | 49 | 8.17 | 1192 | 9 | 5 | 3 | 0 | |
| Kirk Cousins | ATL | 12 | BB | 14 | 112 | 8 | 3508 | 18 | 16 | 2 | 0 |
| Mason Rudolph | TEN | 5 | 5 | 40 | 8 | 1090 | 7 | 5 | 1 | 0 | |
| Marcus Mariota | WAS | 14 | 2 | 14 | 7 | 239 | 2 | 0 | 0 | 0 | |
| Justin Fields | PIT | 9 | 10 | 68 | 6.8 | 1395 | 10 | 1 | 1 | 0 | |
| Andy Dalton | CAR | 11 | 6 | 39 | 6.5 | 1023 | 7 | 6 | 0 | 0 | |
| Daniel Jones | MIN | 6 | AE | 10 | 64 | 6.4 | 2335 | 10 | 7 | 2 | 0 |
| Cooper Rush | DAL | 7 | 10 | 60 | 6 | 1425 | 10 | 3 | 3 | 1 | |
| Anthony Richardson | IND | 14 | BB | 10 | 60 | 6 | 2111 | 12 | 11 | 3 | 1 |
| Tyrod Taylor | NYJ | 12 | 1 | 6 | 6 | 43 | 1 | 0 | 0 | 0 | |
| Malik Willis | GB | 10 | 5 | 28 | 5.6 | 517 | 4 | 0 | 0 | 0 | |
| Bryce Young | CAR | 11 | 11 | 58 | 5.27 | 1940 | 11 | 9 | 2 | 0 | |
| Will Levis | TEN | 5 | 11 | 54 | 4.91 | 2091 | 12 | 12 | 5 | 0 | |
| Aidan O'Connell | LV | 10 | 6 | 28 | 4.67 | 905 | 5 | 3 | 2 | 0 | |
| Gardner Minshew | LV | 10 | 10 | 44 | 4.4 | 2071 | 9 | 10 | 4 | 1 | |
| Deshaun Watson | CLE | 10 | ANJ | 7 | 30 | 4.29 | 1296 | 6 | 3 | 3 | 1 |
| Taysom Hill | NO | 12 | ANJ | 8 | 33 | 4.13 | 486 | 6 | 1 | 1 | 0 |
| Mac Jones | JAC | 12 | 7 | 22 | 3.14 | 1079 | 5 | 7 | 2 | 1 | |
| Tyler Huntley | MIA | 6 | 3 | 9 | 3 | 444 | 2 | 1 | 1 | 0 | |
| Spencer Rattler | NO | 12 | 4 | 8 | 2 | 767 | 2 | 2 | 2 | 0 | |
| Drew Lock | NYG | 11 | 5 | 8 | 1.6 | 543 | 1 | 2 | 1 | 1 | |
| Jacoby Brissett | NE | 14 | 7 | 10 | 1.43 | 890 | 2 | 1 | 1 | 1 | |
| Tim Boyle | NYG | 11 | 3 | 4 | 1.33 | 285 | 1 | 1 | 0 | 0 | |
| Desmond Ridder | LV | 10 | 5 | 6 | 1.2 | 483 | 2 | 2 | 2 | 0 | |
| Jake Haener | NO | 12 | 8 | 4 | 0.5 | 248 | 1 | 1 | 0 | 0 | |
| Tommy DeVito | NYG | 11 | 3 | 1 | 0.33 | 289 | 0 | 0 | 0 | 0 | |
| Brandon Allen | SF | 9 | 3 | 1 | 0.33 | 203 | 1 | 2 | 1 | 0 | |
| Tyson Bagent | CHI | 7 | 4 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | |
| Kyle Allen | PIT | 9 | 1 | 0 | 0 | 19 | 0 | 0 | 0 | 0 | |
| Carson Wentz | KC | 6 | 2 | 0 | 0 | 20 | 0 | 0 | 0 | 0 | |
| Jake Browning | CIN | 12 | 2 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | |
| C.J. Beathard | JAC | 12 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Skylar Thompson | PIT | 9 | 3 | 0 | 0 | 191 | 0 | 0 | 0 | 0 | |
| Michael Penix Jr. | ATL | 12 | 2 | 0 | 0 | 38 | 0 | 0 | 0 | 0 | |
| Hendon Hooker | DET | 5 | 3 | 0 | 0 | 64 | 0 | 0 | 0 | 0 | |
| Kenny Pickett | PHI | 5 | 3 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | |
| Mitchell Trubisky | BUF | 12 | 7 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | |
| Nick Mullens | MIN | 6 | 5 | 0 | 0 | 36 | 0 | 0 | 0 | 0 | |
| Taylor Heinicke | LAC | 5 | 3 | 0 | 0 | 40 | 0 | 0 | 0 | 0 | |
| Jeff Driskel | WAS | 14 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Davis Mills | HOU | 14 | 3 | 0 | 0 | 79 | 0 | 0 | 0 | 0 | |
| Kyle Trask | TB | 11 | 3 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | |
| Jarrett Stidham | DEN | 14 | 3 | 0 | 0 | -2 | 0 | 0 | 0 | 0 | |
| Josh Johnson | BAL | 14 | 4 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | |
| Clayton Tune | ARI | 11 | 5 | -2 | -0.4 | 2 | 0 | 0 | 1 | 0 | |
| Sam Howell | SEA | 10 | 3 | -2 | -0.67 | 26 | 0 | 1 | 0 | 0 | |
| Trey Lance | DAL | 7 | 2 | -2 | -1 | 35 | 0 | 1 | 0 | 0 | |
| Dorian Thompson-Robinson | CLE | 10 | 4 | -6 | -1.5 | 160 | 0 | 3 | 0 | 0 |